Invention Grant
- Patent Title: Macrocyclic immunomodulators
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Application No.: US17338502Application Date: 2021-06-03
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Publication No.: US11691985B2Publication Date: 2023-07-04
- Inventor: Viengkham Malathong , Jeffrey McMahon , Darren J. McMurtrie , Sreenivas Punna , Howard S. Roth , Rajinder Singh , Penglie Zhang
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA San Carlos
- Assignee: CHEMOCENTRYX, INC.
- Current Assignee: CHEMOCENTRYX, INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Amy C. Madl
- Main IPC: C07D498/08
- IPC: C07D498/08 ; A61P37/02 ; A61P31/12 ; A61P31/04 ; A61P31/10 ; A61P35/00

Abstract:
Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II):
including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Public/Granted literature
- US20220119405A1 MACROCYCLIC IMMUNOMODULATORS Public/Granted day:2022-04-21
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