Invention Grant
- Patent Title: Amino deprotection using 3-(diethylamino)propylamine
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Application No.: US17547076Application Date: 2021-12-09
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Publication No.: US11692007B2Publication Date: 2023-07-04
- Inventor: Giulia Martelli , Paolo Cantelmi , Alessandra Tolomelli , Chiara Palladino , Lucia Ferrazzano , Walter Cabri , Marco Macis , Angelo Viola , Antonio Ricci
- Applicant: Alma Mater Studiorum—Università di Bologna , FRESENIUS KABI IPSUM S.R.L.
- Applicant Address: IT Bologna
- Assignee: Alma Mater Studiorum—Università di Bologna,Fresenius Kabi IPSUM S.r.l.
- Current Assignee: Alma Mater Studiorum—Università di Bologna,Fresenius Kabi IPSUM S.r.l.
- Current Assignee Address: IT Bologna; IT Cassina de' Pecchi Milano
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: C07K1/06
- IPC: C07K1/06 ; C07K7/06 ; A61K38/00
Abstract:
The invention provides a method for the cleavage of Fmoc group characterized by using a solution comprising 3-(diethylamino)propylamine. In particular, it provides a method for the preparation of peptides in solid phase wherein Fmoc protected amino acids are used and the Fmoc group is cleaved by a solution comprising 3-(diethylamino)propylamine.
Public/Granted literature
- US20220185842A1 AMINO DEPROTECTION USING 3-(DIETHYLAMINO)PROPYLAMINE Public/Granted day:2022-06-16
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