Invention Grant
- Patent Title: Human cytomegalovirus comprising exogenous antigens
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Application No.: US17214598Application Date: 2021-03-26
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Publication No.: US11692012B2Publication Date: 2023-07-04
- Inventor: Klaus Frueh , Scott G. Hansen , Jay Nelson , Louis Picker , Patrizia Caposio
- Applicant: Oregon Health & Science University
- Applicant Address: US OR Portland
- Assignee: Oregon Health & Science University
- Current Assignee: Oregon Health & Science University
- Current Assignee Address: US OR Portland
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C07K14/045
- IPC: C07K14/045 ; A61K39/12 ; C12N15/86 ; A61K35/33 ; A61K39/00 ; A61K39/39 ; C12N15/85 ; A61K39/21 ; C07K14/16 ; A61P35/00
Abstract:
Human cytomegalovirus vectors comprising heterologous antigens are disclosed. The vectors derived from the TR strain, are ganciclovir sensitive, include active US2, US3, US6, US7 and UL131A genes, and have a deleterious or inactivating mutation in the UL82 gene preventing the expression of pp71.
Public/Granted literature
- US20220064225A1 Human Cytomegalovirus Comprising Exogenous Antigens Public/Granted day:2022-03-03
Information query
