Invention Grant
- Patent Title: Compositions and methods involving engineered p27
-
Application No.: US16977441Application Date: 2019-04-10
-
Publication No.: US11692179B2Publication Date: 2023-07-04
- Inventor: Seth Rubin , Keelan Guiley
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Santa Cruz
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2019/026845 2019.04.10
- International Announcement: WO2019/209538A 2019.10.31
- Date entered country: 2020-09-01
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C07K14/47 ; C12Q1/48
Abstract:
The disclosure provides polypeptides comprising an engineered p27, or a fragment thereof. Such polypeptides may be used to form trimeric protein complexes with a cyclin-dependent kinase 4 (Cdk4) (or a variant thereof) or Cdk6 (or a variant thereof), and a cyclin D (CycD) or a variant thereof.
Public/Granted literature
- US20210002619A1 COMPOSITIONS AND METHODS INVOLVING ENGINEERED P27 Public/Granted day:2021-01-07
Information query
