There is provided a method comprising: mapping patient-specific medications (mapped to active ingredients) and patient-specific parameters of a patient to a mapping data-structure that maps between medications, predicted medical outcomes, and patient parameters, each relationship-mapping includes one medication (active ingredient), one predicted medical outcome, one patient parameter, one risk score, a predicted medical outcome(s) denoting a medication induced event of a corresponding mapped medication, the patient parameter(s) including: a medication influencing factor (for an active ingredient, selected from primary parameters affecting the corresponding mapped medication: blood level, absorption, distribution, metabolism, elimination) directly affecting the corresponding mapped medication which affects the medication induced event, and/or an event influencing factor directly affecting the medication induced event, and computing an aggregated risk score for each respective predicted medical outcome by aggregating the risk scores of the identified relationship-mappings including each respective predicted medical outcome.