A multiple access method, a multiple access transmitter, and a multiple access receiver includes performing, by a transmitter, channel coding on a bit sequence to determine a coded sequence. The method also includes interleaving and/or scrambling the coded sequence, and performing multidimensional constellation modulation on the interleaved and/or scrambled sequence; performing grid mapping on the modulated symbol sequence to determine a mapped sequence, and transmitting the mapped sequence. The method also includes receiving, by a receiver, mixed signals from multiple transmitters, the mixed signals are obtained by performing, by each of the multiple transmitters, interleaving and/or scrambling, multidimensional constellation modulation and grid mapping on data. The method further includes decoding, by the receiver, mixed information according to interleaver information and/or scrambler information, multidimensional constellation information and grid mapping pattern information corresponding to each transmitter to obtain data corresponding to each transmitter.