A drive mechanism, a camera device and a portable electric device are provided. The drive mechanism includes an auto-focusing mechanism and a stabilization mechanism. The auto-focusing mechanism receive and drive the lens along an optical axis of the lens. The auto-focusing mechanism includes a stator and a mover. The mover includes a holder for installing the lens. A groove is formed at a surface of the holder facing the stator. An inner side of the groove is coated with a vibration damping gel. The stator is provided with a claw member extending into the groove to cooperate with the vibration damping gel. The stator is further provided with a through-hole opposite to the groove to expose the groove. After assembling is completed, an amount of the vibration damping gel can be adjusted through the groove, thereby suppressing vibration of the auto-focusing mechanism and improving the vibration damping effect.