Invention Grant
- Patent Title: Tumescent infiltration drug delivery of high subcutaneous drug concentrations with prolonged local and systemic effects and minimal local or systemic toxicity
-
Application No.: US16700740Application Date: 2019-12-02
-
Publication No.: US11696890B2Publication Date: 2023-07-11
- Inventor: Jeffrey Alan Klein , Paytra Alan Klein
- Applicant: HK Pharma
- Applicant Address: US CA San Clemente
- Assignee: HK PHARMA
- Current Assignee: HK PHARMA
- Current Assignee Address: US CA San Clemente
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K31/137 ; A61K9/08 ; A61K45/06 ; A61K31/56 ; A61K31/167 ; A61K31/522 ; A61K31/546 ; A61K31/52 ; A61K31/4164 ; A61K47/02
Abstract:
A tumescent composition comprising a drug or a therapeutic agent in a tumescent solution, wherein a tumescent concentration of the drug or therapeutic agent is simultaneously below a threshold for local, subcutaneous tissue toxicity, above a threshold for positive local therapeutic effect, and above a concentration safely achievable by intravenous (IV), intramuscular (IM) or oral (PO) delivery; and the tumescent solution comprises a vasoconstrictor; a pharmaceutically acceptable carrier; and optionally a local anesthetic, wherein the tumescent solution does not comprise an antibiotic.
Information query
