Invention Grant
- Patent Title: Carboxamide-pyrimidine derivatives as SHP2 antagonists
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Application No.: US17245423Application Date: 2021-04-30
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Publication No.: US11696916B2Publication Date: 2023-07-11
- Inventor: Catherine Jorand-Lebrun , Roch Boivin , Igor Mochalkin , Theresa Johnson , Nina Linde , Doreen Musch , Deepak Kumar
- Applicant: Merck Patent GmbH
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: EMD Serono Research and Development Institute, Inc.
- Agent Nicholas J. Sisti
- Priority: EP 161323 2019.03.07
- The original application number of the division: US16813192 2020.03.09
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/497 ; A61K45/06 ; A61K39/395 ; C07D513/10 ; C07D401/04 ; C07D491/107
Abstract:
The invention relates to carboxamide-pyrimidine derivatives of the general formula I,
or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.
or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.
Public/Granted literature
- US20220362244A1 CARBOXAMIDE-PYRIMIDINE DERIVATIVES AS SHP2 ANTAGONISTS Public/Granted day:2022-11-17
Information query
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