Invention Grant
- Patent Title: Process for synthesis of eliglustat and intermediate compounds thereof
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Application No.: US16496008Application Date: 2017-10-16
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Publication No.: US11697644B2Publication Date: 2023-07-11
- Inventor: Yu Liu , Guanneng Yu , Zhiguo Zheng
- Applicant: ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD.
- Applicant Address: CN Zhejiang
- Assignee: ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD.
- Current Assignee: ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD.
- Current Assignee Address: CN Zhejiang
- Agency: Ladas & Parry LLP
- Priority: CN 1710169305.9 2017.03.21
- International Application: PCT/CN2017/106348 2017.10.16
- International Announcement: WO2018/171173A 2018.09.27
- Date entered country: 2019-09-20
- Main IPC: C07D319/18
- IPC: C07D319/18 ; A61K31/40 ; A61K31/357 ; C07C231/00 ; C07C209/26 ; C07D207/04 ; A61K31/16 ; C07D405/06 ; C07D413/06

Abstract:
A method for synthesis of Eliglustat and intermediate compounds thereof. Specifically, a method for synthesis of Eliglustat and pharmaceutically acceptable salts thereof, and further to intermediate compounds used in the method and a preparation method for the intermediate compounds. Compared with an existing synthesis method, the method for synthesis of Eliglustat of the present invention uses novel synthetic intermediates and synthesis steps, features ease of operation, high yield, good purity of intermediates and target products, etc., and facilitates industrial production.
Public/Granted literature
- US20200031808A1 PROCESS FOR SYNTHESIS OF ELIGLUSTAT AND INTERMEDIATE COMPOUNDS THEREOF Public/Granted day:2020-01-30
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