In a system of manufacturing an orthodontic wire, a method for manufacturing the orthodontic wire using the system, and an orthodontic wire bending machine for performing the system, the system includes a teeth data obtaining part, a simulating part, a calculating part and a wire manufacturing part. The teeth data obtaining part obtains present teeth data of a patient. The simulating part generates final teeth data. The calculating part compares a predetermined threshold to a compared value between the present teeth data of the patient and the final teeth data. The wire manufacturing part selectively manufactures a wire for an orthodontic process or a wire for a dentition maintenance process based on a compared result of the calculating part.