An air vent for a vehicle may include: a duct part having an internal path through which air is moved; a first adjusting part rotatably installed in the duct part, and configured to guide the discharge direction of the air while rotated in a side-to-side direction; a second adjusting part rotatably installed in the duct part with the first adjusting part, and configured to guide the discharge direction of the air or block an air flow passing through the duct part, while rotated in a top-to-bottom direction; and an airtightness maintaining part fixed to the duct part facing the second adjusting part, and configured to block the movement of the air while brought into contact with the second adjusting part for opening/closing the duct part.