Invention Grant
- Patent Title: Inhibitors of NLRP3 inflammasome
-
Application No.: US17701856Application Date: 2022-03-23
-
Publication No.: US11702391B2Publication Date: 2023-07-18
- Inventor: George Hartman , Xu He , Jia Du , Lifang Zhang , Paul Humphries , Kevin Edward Leif Wilhelmsen
- Applicant: BioAge Labs, Inc. , HITGEN, INC.
- Applicant Address: US CA Richmond
- Assignee: BIOAGE LABS, INC.,HITGEN, INC.
- Current Assignee: BIOAGE LABS, INC.,HITGEN, INC.
- Current Assignee Address: US CA Richmond; CN Sichuan
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque; Nicole Sassu
- Main IPC: C07D231/56
- IPC: C07D231/56 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; C07D417/12 ; C07D235/06 ; C07D413/12 ; C07D471/04

Abstract:
The present disclosure relates to compounds of Formula I:
that act as inhibitors of NLRP3 inflammasomes; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with inflammation and inflammaging, including hearing loss and other diseases associated with aging.
that act as inhibitors of NLRP3 inflammasomes; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with inflammation and inflammaging, including hearing loss and other diseases associated with aging.
Public/Granted literature
- US20220324812A1 INHIBITORS OF NLRP3 INFLAMMASOME Public/Granted day:2022-10-13
Information query