Invention Grant
- Patent Title: Salt types, crystal forms, and preparation methods for benzopyrazole compounds as RHO kinase inhibitors
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Application No.: US17767104Application Date: 2020-10-16
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Publication No.: US11702400B2Publication Date: 2023-07-18
- Inventor: Lingyun Wu , Zheming Xiao , Chunyan Jiang , Jian Li , Shuhui Chen
- Applicant: MEDSHINE DISCOVERY INC.
- Applicant Address: CN Jiangsu
- Assignee: MEDSHINE DISCOVERY INC.
- Current Assignee: MEDSHINE DISCOVERY INC.
- Current Assignee Address: CN Jiangsu
- Agency: Houston Beshining Law Office PLLC
- Agent Liangang Ye
- Priority: CN 1910993446.1 2019.10.18
- International Application: PCT/CN2020/121388 2020.10.16
- International Announcement: WO2021/073592A 2021.04.22
- Date entered country: 2022-04-07
- Main IPC: C07D401/04
- IPC: C07D401/04

Abstract:
Salt types, crystal forms, and preparation methods for benzopyrazole compounds as RHO kinase inhibitors. Specifically, disclosed are hydrochloride and acetate of compounds of formula (I) and crystal forms thereof, as well as application of the salt types and the crystal forms in preparation of RHO inhibitor drugs.
Public/Granted literature
- US20220380336A1 SALT TYPES, CRYSTAL FORMS, AND PREPARATION METHODS FOR BENZOPYRAZOLE COMPOUNDS AS RHO KINASE INHIBITORS Public/Granted day:2022-12-01
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