Invention Grant
- Patent Title: 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
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Application No.: US16486541Application Date: 2018-02-15
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Publication No.: US11702408B2Publication Date: 2023-07-18
- Inventor: Aimee Crombie Speerschneider , Dennis Shinji Yamashita , Philip Michael Pitis , Michael John Hawkins , Guodong Liu , Tamara Ann Miskowski Daubert , Catherine C. K. Yuan , Robert Borbo Kargbo , Robert Jason Herr , Donna Romero
- Applicant: Trevena, Inc.
- Applicant Address: US PA Chesterbrook
- Assignee: TREVENA, INC.
- Current Assignee: TREVENA, INC.
- Current Assignee Address: US PA Chesterbrook
- Agency: Goodwin Procter LLP
- International Application: PCT/US2018/018312 2018.02.15
- International Announcement: WO2018/152293A 2018.08.23
- Date entered country: 2019-08-16
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D403/14 ; A61P25/22 ; A61P25/24 ; A61P25/06 ; A61P29/00
Abstract:
The present embodiments are directed, in part, to 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, such as those of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinson's Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.
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