Invention Grant
- Patent Title: Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same
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Application No.: US16978117Application Date: 2019-03-11
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Publication No.: US11702427B2Publication Date: 2023-07-18
- Inventor: Shuai Chen , Bruce D. Dorsey , Yi Fan , Dimitar B. Gotchev , Jorge Quintero
- Applicant: Arbutus Biopharma Corporation
- Applicant Address: CA Burnaby
- Assignee: Arbutus Biopharma Corporation
- Current Assignee: Arbutus Biopharma Corporation
- Current Assignee Address: CA Burnaby
- Agency: Saul Ewing LLP
- Agent Domingos J. Silva; Kevin T. O'Brien
- International Application: PCT/US2019/021557 2019.03.11
- International Announcement: WO2019/177937A 2019.09.13
- Date entered country: 2020-09-03
- Main IPC: C07D493/04
- IPC: C07D493/04 ; C07D215/02 ; C07D221/04 ; C07D471/04 ; C07D493/14

Abstract:
The present invention includes in one aspect substituted 2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carboxylic acids, analogues thereof, and compositions comprising the same, which can be used to treat and/or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) in a patient. In certain embodiments, the invention provides a compound of formula (I), or a salt, solvate, geometric isomer, stereoisomer, tautomer, and any mixtures thereof:
Public/Granted literature
- US20210017186A1 SUBSTITUTED 2-PYRIDONE TRICYCLIC COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME Public/Granted day:2021-01-21
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