Invention Grant
- Patent Title: Spirobicyclic analogues
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Application No.: US17344261Application Date: 2021-06-10
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Publication No.: US11702441B2Publication Date: 2023-07-18
- Inventor: Jonas Verhoeven , Guido Alfons F. Verniest , Johannes Wilhelmus John F. Thuring , Tongfei Wu , Vineet Pande , Lieven Meerpoel , Dirk Brehmer , Weimei Sun , Scott E. Denmark
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agency: BakerHostetler
- Priority: EP 163867 2018.03.26
- Main IPC: C07H19/167
- IPC: C07H19/167
Abstract:
The present invention relates to novel spirobicyclic analogues of Formula (I)
wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Public/Granted literature
- US20210380627A1 Novel Spirobicyclic Analogues Public/Granted day:2021-12-09
Information query
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