A spinning machine and associated operational method include a plurality of adjacently arranged workstations that each have a spinning device for making a thread and a suction nozzle for seeking a thread end on a package. A first suction system includes a first vacuum source and a first vacuum duct extending along the workstations, the spinning devices of the workstations connected to the first suction system. A second suction system includes a second vacuum source and a second vacuum duct extending along the workstations, the suction nozzles of at least a first partial number of the workstations connected to the second suction system. The first suction system and the second suction system are pneumatically completely disconnected from one another.