A grouting device for high-coagulability grouting materialsincludes a grouting pipe, a connector and a self-sealing pipe head, wherein one end of the connector is connected with a grouting pump through the grouting pipe, the other end of the connector is connected with the self-sealing pipe head through the grouting pipe, and the grouting pipe is connected with the connector and the self-sealing pipe head in a fixed and sealed mode. The grouting device is easy to install, features reliable connection between the grouting pipe and the connector and the self-sealing pipe head, and can be reused. Because the inner diameter of the connector is consistent with the inner diameter of the grouting pipe, and a slurry outlet on an end cap of the self-sealing pipe head is a circular slurry outlet, pressure loss in the grouting process is effectively reduced, and the grouting effect is good.