A client application establishes a connection between the client application and an origin server over one or more networks. The application generates a request to establish a secure session with the origin server over the connection. The request includes information, in a header of the request, that flags traffic sent during the secure session to a network of the one or more networks as subject to one or more optimizations performed by the network. Subsequent to establishing the secure session, the application encrypts the traffic in accordance with the secure session and sends the traffic to the origin server over the connection, subject to the one or more optimizations. The infrastructure service applies the one or more optimizations to the traffic as it passes through the edge network to the origin server.