A tactile sense presentation device includes a panel that includes a support substrate, a plurality of electrodes, which are formed on the support substrate, extending in a predetermined direction, and an insulating layer covering the plurality of electrodes; and a drive unit that drives the panel, wherein a tactile sense is presented to an operator based on an electrostatic force generated between the electrodes and the operator by the drive unit applying a signal of a voltage to the electrode, a contact face of the insulating layer that is in contact with the operator has a surface roughness Ra of a predetermined range, and the voltage applied to the electrodes corresponding to an area in which the tactile sense is presented to the operator is a voltage corresponding to the surface roughness Ra of the contact face.