An ear nose and throat (ENT) imaging and analysis system includes an endoscope usable to capture images of the nasal canal and other aspects of patient anatomy. Endoscopic images may be presented to a user via a touchscreen display, and the software may provide different imaging modes that aid in identifying particular anatomical structures or areas within the nasal canal. In one mode, the system uses an object recognition process to identify the nasal valve opening within the images at a relaxed state, and during forceful inhalation, and then calculates the difference between the two states, which may be suggestive of nasal valve collapse. In other modes, the system is configured to identify abnormalities of the inferior turbinate, septum, or other anatomy, as well as empty spaces within the nasal canal, as well as areas and volumes of empty space and user defined boundaries.