The present invention relates to the field of medical monitoring, and in particular non-contact video monitoring to measure tidal volume of a patient. Systems, methods, and computer readable media are described for determining a region of interest of a patient and monitoring that region of interest to determine tidal volume of the patient. This may be accomplished using a depth sensing camera to monitor a patient and determine how their chest and/or other body parts are moving as the patient breathes. This sensing of movement can be used to determine the tidal volume measurement.