Invention Grant
- Patent Title: Mebendazole prodrugs with enhanced solubility and oral bioavailability
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Application No.: US16967924Application Date: 2019-02-08
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Publication No.: US11712435B2Publication Date: 2023-08-01
- Inventor: Barbara Slusher , Rana Rais , Gregory Riggins , Pavel Majer , Tomas Tichy , Jan Vavra , Andrej Jancarik , Lukas Tenora
- Applicant: The Johns Hopkins University , Institute of Organic Chemistry and Biochemistry AS CR v.v.i.
- Applicant Address: US MD Baltimore
- Assignee: THE JOHNS HOPKINS UNIVERSITY,INSTITUTE OF ORGANIC CHEMISTRY & BIOCHEMISTRY AS CR V.V.I.
- Current Assignee: THE JOHNS HOPKINS UNIVERSITY,INSTITUTE OF ORGANIC CHEMISTRY & BIOCHEMISTRY AS CR V.V.I.
- Current Assignee Address: US MD Baltimore; CZ Prague
- Agency: Casimir Jones, S.C.
- Agent Jeffrey W. Childers
- International Application: PCT/US2019/017291 2019.02.08
- International Announcement: WO2019/157338A 2019.08.15
- Date entered country: 2020-08-06
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; A61K31/685 ; A61K31/7056 ; C07D235/32 ; C07D405/12 ; C07F9/6506 ; A61P35/00 ; C07H13/12 ; A61K31/675 ; A61K45/06 ; C07H15/26
Abstract:
Prodrugs of mebendazole and methods for their use in treating a disease, disorder, or disorder, including cancer, are disclosed.
Public/Granted literature
- US20210205271A1 MEBENDAZOLE PRODRUGS WITH ENHANCED SOLUBILITY AND ORAL BIOAVAILABILITY Public/Granted day:2021-07-08
Information query
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