Invention Grant
- Patent Title: Methods and materials for identifying and treating bet inhibitor-resistant cancers
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Application No.: US16637674Application Date: 2018-08-09
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Publication No.: US11712439B2Publication Date: 2023-08-01
- Inventor: Haojie Huang , Yinghao Sun , Shancheng Ren
- Applicant: Mayo Foundation for Medical Education and Research , Shanghai Changhai Hospital
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research,Shanghai Changhai Hospital
- Current Assignee: Mayo Foundation for Medical Education and Research,Shanghai Changhai Hospital
- Current Assignee Address: US MN Rochester; CN Shangahi Shi
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2018/045976 2018.08.09
- International Announcement: WO2019/032810A 2019.02.14
- Date entered country: 2020-02-07
- Main IPC: A61K31/517
- IPC: A61K31/517 ; A61K31/4375 ; A61K31/551 ; A61P35/00 ; C12Q1/6886 ; A61K45/06
Abstract:
This document provides methods and materials involved in identifying and treating mammals having a cancer resistant to BET inhibitors. For example, methods and materials for administering one or more AKT inhibitors in combination with one or more BET inhibitors to mammals identified as having a cancer resistant to treatment with one or more BET inhibitors in the absence of AKT inhibitors are provided.
Public/Granted literature
- US20210361653A1 METHODS AND MATERIALS FOR IDENTIFYING AND TREATING BET INHIBITOR-RESISTANT CANCERS Public/Granted day:2021-11-25
Information query
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