Invention Grant
- Patent Title: Long-acting polypeptide composition for treating atrial fibrillation and its application
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Application No.: US17931117Application Date: 2022-09-10
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Publication No.: US11712461B2Publication Date: 2023-08-01
- Inventor: Yue Wu , Kaiyue Feng , Chaofeng Sun
- Applicant: Yue Wu , Kaiyue Feng , Chaofeng Sun
- Applicant Address: CN Xi'an
- Assignee: THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY
- Current Assignee: THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY
- Current Assignee Address: CN Xi'an
- Priority: CN 2111084913.2 2021.09.16
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61P9/06 ; C07K14/00
Abstract:
A polypeptide composition for treating atrial fibrillation includes a polypeptide that has a sequence: fADNYTRLRKQMAVKKYLNSILN-NH2 (SEQ ID NO: 1),
From an N-terminus of the polypeptide, a first amino acid (f) is a D-Phe, a second amino acid is Ala, and a third amino acid is Asp; and the peptide is linear in a solution and forms an α-helix structure after encountering a lipid bilayer.
From an N-terminus of the polypeptide, a first amino acid (f) is a D-Phe, a second amino acid is Ala, and a third amino acid is Asp; and the peptide is linear in a solution and forms an α-helix structure after encountering a lipid bilayer.
Public/Granted literature
- US20230131922A1 LONG-ACTING POLYPEPTIDE COMPOSITION FOR TREATING ATRIAL FIBRILLATION AND ITS APPLICATION Public/Granted day:2023-04-27
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