Printheads and methods of operation. In one embodiment, a printhead includes a plurality of jetting channels comprising first jetting channels configured to jet a first print fluid and second jetting channels configured to jet a second print fluid, and a driver circuit communicatively coupled to actuators of the jetting channels. The driver circuit receives a drive waveform comprising first jetting pulses provisioned for the first print fluid and second jetting pulses provisioned for the second print fluid, and gating signals comprising a first active gating signal designated for jetting the first print fluid and a second active gating signal designated for jetting the second print fluid. The driver circuit selectively applies the first jetting pulses to actuators of the first jetting channels based on the first active gating signal, and selectively applies the second jetting pulses to actuators of the second jetting channels based on the second active gating signal.