A method of reducing the noise generated in-flight by a vortex wake caused by each first blade of a main rotor of a hybrid helicopter. The hybrid helicopter includes a main rotor, at least two wings and at least one propeller. The method enables a stabilized flight phase on the level or with a non-zero aerodynamic slope to be implemented by determining a first value of the pitch of the second blades of each propeller and an angle of incidence of the main rotor as function of the flight conditions, then by applying the first pitch value to each propeller and by applying the angle of incidence to the main rotor so as to direct the vortex wake to limit the noisy interactions between the vortex wake and the other first blades and/or the second blades.