Invention Grant
- Patent Title: Methods for producing hepatocytes
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Application No.: US16902368Application Date: 2020-06-16
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Publication No.: US11713448B2Publication Date: 2023-08-01
- Inventor: Louise Kristina Hagbard , Carl Gunnar Jesper Ericsson , Katherine Rachel Cameron , David Colin Hay , Stuart John Forbes , Hassan Rashidi
- Applicant: BioLamina AB , The University of Edinburgh
- Applicant Address: SE Sundyberg
- Assignee: BIOLAMINA AB
- Current Assignee: BIOLAMINA AB
- Current Assignee Address: SE Sundyberg
- Agency: Lippes Mathias LLP
- The original application number of the division: US15338352 2016.10.29
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/095 ; C12N5/074 ; C12N5/071
Abstract:
Methods for producing hepatocytes from pluripotent human stem cells are disclosed herein. The stem cells are plated on a cell culture substrate comprising two laminins. The stem cells are then exposed to different cell culture mediums to induce differentiation. The resulting hepatocytes have higher metabolic capacity compared to hepatocytes cultured on different substrates.
Public/Granted literature
- US20200308551A1 METHODS FOR PRODUCING HEPATOCYTES Public/Granted day:2020-10-01
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