Invention Grant
- Patent Title: Means and methods for modifying multiple alleles
-
Application No.: US16311561Application Date: 2017-06-20
-
Publication No.: US11713458B2Publication Date: 2023-08-01
- Inventor: Karina Nawrath , Janine Guendel , Sven Bahrke , Lars Stoeckl , Steffen Goletz
- Applicant: Octapharma AG
- Applicant Address: CH Lachen
- Assignee: Octapharma AG
- Current Assignee: Octapharma AG
- Current Assignee Address: CH Lachen
- Agency: Kagan Binder, PLLC
- Priority: EP 001385 2016.06.20 LU 251 2016.10.07
- International Application: PCT/EP2017/065010 2017.06.20
- International Announcement: WO2017/220527A 2017.12.28
- Date entered country: 2018-12-19
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N9/22 ; C12N9/64 ; C12N15/10 ; C12P21/00 ; C12N15/113
Abstract:
The present invention relates to a method of modifying at least one gene in a cell via CRISPR/Cas, wherein the at least one gene has at least three alleles. The present invention further relates to cells obtainable by the method of the invention. Additionally, the present invention provides a method of producing a protein in a cell obtainable by the method of modifying at least one gene of the invention. Moreover, the invention relates to proteins obtainable by the method of producing a protein and use thereof, for example in therapy.
Public/Granted literature
- US20190185848A1 MEANS AND METHODS FOR MODIFYING MULTIPLE ALLELES Public/Granted day:2019-06-20
Information query
IPC分类:
