Invention Grant
- Patent Title: Biomarker panel and methods for detecting microsatellite instability in cancers
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Application No.: US16767968Application Date: 2019-01-22
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Publication No.: US11713488B2Publication Date: 2023-08-01
- Inventor: Bram De Craene , Klaas Decanniere , Jan Van De Velde , Geert Maertens
- Applicant: Biocartis NV
- Applicant Address: BE Mechelen
- Assignee: BIOCARTIS NV
- Current Assignee: BIOCARTIS NV
- Current Assignee Address: BE Mechelen
- Agency: Quarles & Brady LLP
- Priority: EP 153056 2018.01.23 EP 168304 2018.04.19
- International Application: PCT/EP2019/051515 2019.01.22
- International Announcement: WO2019/145306A 2019.08.01
- Date entered country: 2020-05-28
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886
Abstract:
The present invention generally relates to the field of cancer, in particular to cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency. Examples of such cancers include many colorectal, gastric, and endometrial tumors. Accordingly, the present invention provides a novel diagnostic marker panel for analyzing MSI loci, together with methods and kits of using said panel in the detection of cancers having microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency.
Information query
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