An SPD-based memory monitoring and service life prediction method and system. Said method includes: acquiring parameter information of each memory bank in a server, and setting a weight for the parameter information; reading configuration information of each memory bank, and calculating occupation ratio information of parameters of each memory bank according to the configuration information and the parameter information; calculating state information of each memory bank according to the weight and the occupation ratio information; determining an influence factor according to the number of CPUs in the server and the number and position of memory banks in each CPU; and calculating a final memory state value according to the influence factor and the state information, and according to the used time and the state information of each memory bank, calculating the remaining service life of each memory bank by means of piecewise fitting using a least square method.