Various embodiments include systems and methods of arthropod detection using an electronic arthropod detection device. The electronic arthropod detection device may scan a surface or a subject using one or both of a hyperspectral image sensor or a multispectral image sensor that is sensitive to multiple bands of electromagnetic radiation to detect the presence or likely presence of an arthropod in a region of interest (ROI). A camera sensitive to a visible band of electromagnetic radiation may be used to capture at least one image and provides the image(s) to an object detection model in response to determining that an arthropod is or is likely present in the ROI. Hyperspectral and/or multispectral images may be provided to the object detection model alone or in combination with visible light image(s). A processor may initiate an arthropod detected procedure in response to detecting an arthropod in the ROI.