Disclosed is a device (100) for treatment of anal fistula. The device comprises a hollow wire (110) comprising a first end (112) and a second end (114) opposite to the first end, the hollow wire is operable to be received by a fistula track with both first and second ends projecting out of the fistula track. The device also comprises an insert (120) operable to be partially inserted into the first end of the hollow wire and to project out of the first end. The device further comprises an applicator (130) operable to be removably arranged on the second end of the hollow wire when the hollow wire is placed in the fistula track. The applicator is operable to be held for enabling the projected out insert to be inserted into second end for detachably coupling the first and second ends to form a closed loop around the fistula track.