Invention Grant
- Patent Title: Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions
-
Application No.: US17153749Application Date: 2021-01-20
-
Publication No.: US11717522B2Publication Date: 2023-08-08
- Inventor: Peter Scheurer , Frank Tegtmeier , Reinhard Schinzel
- Applicant: VASOPHARM GMBH
- Applicant Address: DE Wuerzburg
- Assignee: VASOPHARM GMBH
- Current Assignee: VASOPHARM GMBH
- Current Assignee Address: DE Wuerzburg
- Agency: Acuity Law Group, PC
- Agent Michael A. Whittaker
- Priority: EP 162727 2014.03.31
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K47/02 ; A61K9/19 ; A61K9/00 ; A61K31/4985
Abstract:
The present invention relates to a method for preparing a lyophilized solid pharmaceutical composition comprising
a) a compound having the formula (I):
and/or a compound having the formula (II):
and
b) two different sodium phosphate salts, wherein the two different sodium phosphate salts are NaH2PO4·2H2O and Na2HPO4·2H2O, and wherein the quantity of the NaH2PO4·2H2O and Na2HPO4·2H2O present in the composition is chosen such that the molar ratio of both NaH2PO4·2H2O and Na2HPO4·2H2O to compound (I) or compound (II) ranges from 0.02 to 0.5.
a) a compound having the formula (I):
and/or a compound having the formula (II):
and
b) two different sodium phosphate salts, wherein the two different sodium phosphate salts are NaH2PO4·2H2O and Na2HPO4·2H2O, and wherein the quantity of the NaH2PO4·2H2O and Na2HPO4·2H2O present in the composition is chosen such that the molar ratio of both NaH2PO4·2H2O and Na2HPO4·2H2O to compound (I) or compound (II) ranges from 0.02 to 0.5.
Public/Granted literature
- US20220031703A9 SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS Public/Granted day:2022-02-03
Information query
IPC分类:
