Invention Grant
- Patent Title: Using tumor-navigating
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Application No.: US17433225Application Date: 2020-02-20
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Publication No.: US11717542B2Publication Date: 2023-08-08
- Inventor: Wei Kong , Lingchen Fu , Yixin Shi , Bo Ning
- Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Applicant Address: US AZ Scottsdale
- Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee Address: US AZ Scottsdale
- Agency: Quarles & Brady LLP
- International Application: PCT/US2020/019110 2020.02.20
- International Announcement: WO2020/172461A 2020.08.27
- Date entered country: 2021-08-23
- Main IPC: A61K35/74
- IPC: A61K35/74 ; A61P35/00 ; C07K14/255 ; C12N1/20 ; C12N9/12
Abstract:
The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating and to alter tumor metabolism in the tumor microenvironment. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
Public/Granted literature
- US20210386795A1 USING TUMOR-NAVIGATING SALMONELLA TO MODULATE TUMOR METABOLISM Public/Granted day:2021-12-16
Information query
