Invention Grant
- Patent Title: Iterative discovery of neoepitopes and adaptive immunotherapy and methods therefor
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Application No.: US16713680Application Date: 2019-12-13
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Publication No.: US11717564B2Publication Date: 2023-08-08
- Inventor: Stephen Charles Benz , Kayvan Niazi , Patrick Soon-Shiong , Andrew Nguyen
- Applicant: NANTOMICS, LLC
- Applicant Address: US CA Culver City
- Assignee: NantOmics, LLC
- Current Assignee: NantOmics, LLC
- Current Assignee Address: US CA Culver City
- Agency: Umberg Zipser LLP
- Agent Martin Fessenmaier
- Main IPC: A61K39/00
- IPC: A61K39/00 ; G01N33/574 ; G16H20/00 ; G16H20/40 ; G16H70/60 ; G16B20/20 ; G16B30/10 ; G16B20/00

Abstract:
Contemplated cancer treatments comprise recursive analysis of patient-, cancer-, and location-specific neoepitopes from various biopsy sites of a patient after treatment or between successive rounds of immunotherapy and/or chemotherapy to inform further immunotherapy. Recursive analysis preferably includes various neoepitope attributes to so identify treatment relevant neoepitopes.
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