Invention Grant
- Patent Title: Inhibitors of receptor interacting protein kinase I for the treatment of disease
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Application No.: US17014184Application Date: 2020-09-08
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Publication No.: US11718612B2Publication Date: 2023-08-08
- Inventor: Richard T. Lewis , Matthew Hamilton , William J. Ray , Fernando Alvarez , Naphtali Reyna , Jason Cross , Suyambu Kesava Vijayan Ramaswamy
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Cynthia Hathaway; Lauren L. Stevens; Erik M. Larsen
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04 ; A61K31/4035 ; A61K31/407 ; A61K31/415 ; A61K31/4172 ; A61K31/4196 ; A61K31/4245 ; A61K31/437 ; A61K31/497 ; A61K31/4985 ; A61K31/5383 ; A61K31/551 ; A61K45/06 ; C07D209/44 ; C07D231/44 ; C07D233/90 ; C07D249/14 ; C07D403/06 ; C07D403/12 ; C07D413/12 ; C07D498/04
Abstract:
Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
Public/Granted literature
- US20210094951A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE Public/Granted day:2021-04-01
Information query
