Invention Grant
- Patent Title: Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same
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Application No.: US17207161Application Date: 2021-03-19
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Publication No.: US11718637B2Publication Date: 2023-08-08
- Inventor: Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Richard L. Mackman , Devan Naduthambi , Neil H. Squires
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H19/16 ; A61P31/18 ; A61K31/7076 ; A61K45/06 ; C07H19/20
Abstract:
The present disclosure provides prodrugs of 4′-C-substituted-2-halo-2′-deoxyadenoside nucleosides, and compositions, methods, and kits thereof. Such compounds can be useful for treating viral infections including, but not limited to, human immunodeficiency virus.
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