Invention Grant
- Patent Title: Method for in vitro glycoengineering of an erythropoiesis stimulating protein
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Application No.: US17124254Application Date: 2020-12-16
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Publication No.: US11718653B2Publication Date: 2023-08-08
- Inventor: Maria Maier , Marco Thomann
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Cindy S. Shu
- Priority: EP 161883 2017.03.20
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C12P21/02 ; C07K14/505

Abstract:
The present invention relates to a method for the production of in vitro glycoengineered erythropoiesis stimulating protein, comprising the steps of providing sialic acid free erythropoiesis stimulating protein, treating the erythropoiesis stimulating protein with N-Acetyl-Glucosamin-transferase B3GNT2, treating the erythropoiesis stimulating protein with galactosyltransferase, and treating the erythropoiesis stimulating protein with sialyltransferase.
Public/Granted literature
- US20210101950A1 METHOD FOR IN VITRO GLYCOENGINEERING OF AN ERYTHROPOIESIS STIMULATING PROTEIN Public/Granted day:2021-04-08
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