Invention Grant
- Patent Title: EML4-ALK gene mutation analysis method
-
Application No.: US16631324Application Date: 2018-07-17
-
Publication No.: US11718882B2Publication Date: 2023-08-08
- Inventor: Byung Hee Jeon
- Applicant: CYTOGEN, INC.
- Applicant Address: KR Seoul
- Assignee: CYTOGEN, INC.
- Current Assignee: CYTOGEN, INC.
- Current Assignee Address: KR Seoul
- Agency: Sughrue Mion, PLLC
- Priority: KR 20170099591 2017.08.07
- International Application: PCT/KR2018/008046 2018.07.17
- International Announcement: WO2019/031722A 2019.02.14
- Date entered country: 2020-01-15
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; C12Q1/6806 ; C12Q1/6827

Abstract:
qRT-PCR primers capable of detecting EML4-ALK gene variant based on circulating tumor cells at a more sensitive detection limit than a conventional method. Also disclosed is a lung cancer patient screening method which is capable of detecting EML4-ALK gene variant using circulating tumor cells even in a lung cancer patient on whom ALK-FISH testing has been difficult to perform, due to difficulty in collecting a solid lung cancer tissue sample, and is able to determine whether an anticancer drug targeting the EML4-ALK gene variant may be applied to the lung cancer patient.
Information query
IPC分类: