Invention Grant
- Patent Title: Spatially resolved ligand-receptor binding assays
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Application No.: US17711375Application Date: 2022-04-01
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Publication No.: US11719641B2Publication Date: 2023-08-08
- Inventor: Qiaoqiao Ruan , Sylvia C. Saldana , Joseph P. Skinner , Sergey Y. Tetin
- Applicant: Abbott Laboratories
- Applicant Address: US IL Abbott Park
- Assignee: ABBOTT LABORATORIES
- Current Assignee: ABBOTT LABORATORIES
- Current Assignee Address: US IL Abbott Park
- Agency: Casimir Jones SC
- Agent Lisa Mueller
- Main IPC: G01N21/64
- IPC: G01N21/64 ; G01N33/543
Abstract:
A method for analyzing the results of a ligand-receptor binding assay comprising the steps of:
(a) providing the results of a ligand-receptor binding assay; and
(b) qualifying the results of a ligand-receptor binding assay.
More particularly, the ligand-receptor binding assay involves the steps of combining appropriate reagents in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is directly proportional to the amount of ligand present in the sample. Alternatively, the ligand-receptor binding assay involves the steps of combining appropriate reagents to perform a ligand-receptor binding assay in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is inversely proportional to the amount of analyte present in the sample.
(a) providing the results of a ligand-receptor binding assay; and
(b) qualifying the results of a ligand-receptor binding assay.
More particularly, the ligand-receptor binding assay involves the steps of combining appropriate reagents in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is directly proportional to the amount of ligand present in the sample. Alternatively, the ligand-receptor binding assay involves the steps of combining appropriate reagents to perform a ligand-receptor binding assay in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is inversely proportional to the amount of analyte present in the sample.
Public/Granted literature
- US20220228990A1 SPATIALLY RESOLVED LIGAND-RECEPTOR BINDING ASSAYS Public/Granted day:2022-07-21
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