Radio frequency (RF) communication systems with interference cancellation for coexistence are provided herein. In certain embodiments, an RF communication system includes a transmitter including a power amplifier that amplifies an RF transmit signal to generate an amplified RF transmit signal, a receiver including a low noise amplifier (LNA) that amplifies an RF receive signal, and an interference cancellation circuit. The interference cancellation circuit includes a filter that generates an analog interference cancellation signal based on filtering the amplified radio frequency transmit signal, a controllable phase circuit that provides a phase adjustment to the analog interference cancellation signal, and a controllable gain circuit that provides a gain adjustment to the analog interference cancellation signal. The interference cancellation circuit injects the analog interference cancellation signal into the LNA to compensate the receiver for interference arising from the transmitter.