Invention Grant
- Patent Title: Traditional Chinese medicine composition for treating metabolic syndrome and preparations thereof
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Application No.: US17274968Application Date: 2019-09-17
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Publication No.: US11744870B2Publication Date: 2023-09-05
- Inventor: Ximing Liu , Hong Li
- Applicant: JIANGSU JIUXU PHARMACEUTICAL CO., LTD. , Hong Li
- Applicant Address: CN Jiangsu
- Assignee: JIANGSU JIUXU PHARMACEUTICAL CO., LTD.,Hong Li
- Current Assignee: JIANGSU JIUXU PHARMACEUTICAL CO., LTD.,Hong Li
- Current Assignee Address: CN Jiangsu; CN Jiangsu
- Agency: Paratus Law Group, PLLC
- Priority: CN 1811080557.5 2018.09.17
- International Application: PCT/CN2019/106196 2019.09.17
- International Announcement: WO2020/057503A 2020.03.26
- Date entered country: 2021-03-10
- Main IPC: A61K36/718
- IPC: A61K36/718 ; A61P3/10 ; A61K31/366 ; A61K31/4375 ; A61K31/7048 ; A61K36/062 ; A61K36/428 ; A61K36/54 ; A61K36/752 ; A61K36/8888

Abstract:
Disclosed are a traditional Chinese medicine composition and a traditional Chinese medicine extract composition for treating metabolic syndrome. The traditional Chinese medicine composition consists of the following raw materials in the following weight ratio: 5-80% of Coptidis Rhizoma, 5-70% of Aurantii Fructus Immaturus, 0-60% of Pinelliae Rhizoma, 0-40% of Trichosanthis Fructus, 0-12% of Cinnamomi Cortex, and 10-60% of red yeast rice. The traditional Chinese medicine extract composition consists of the following raw materials in the following weight ratio: 2-30% of Coptidis Rhizoma extract, and 70-98% of a mixed extract from five traditional Chinese medicines comprising Aurantii Fructus Immaturus, Pinelliae Rhizoma, red yeast rice, Trichosanthis Fructus, and Cinnamomi Cortex. The traditional Chinese medicine composition or the traditional Chinese medicine extract composition contains the following active ingredients (mg/g): 6-122 mg/g of total alkaloids, which comprises 4-89 mg/g of berberine, 30-315 mg/g of total flavonoids, which comprises 20-186 mg/g of neohesperidin: and 0.5-9 mg/g of lovastatin. Further provided are preparation methods and applications of the above compositions.
Public/Granted literature
- US20220031791A1 TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING METABOLIC SYNDROME AND PREPARATIONS THEREOF Public/Granted day:2022-02-03
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