A vehicle body structure 10 formed a first ridgeline 35, a second ridgeline 36, and a concave portion 33 in a roof side inner panel 26 of a roof side rail 16. The first ridgeline continuously extends from a front end to a rear end of the roof side rail so that a load input from a front and rear direction of a vehicle body is able to be transmitted to the roof side rail. A second ridgeline includes a bent portion 38 which is recessed toward a first ridgeline to form a concave portion at a position matching a roof arch connection portion in the front and rear direction of the vehicle body. An upper end portion of a center pillar 14 is joined to the concave portion.