The present disclosure relates to glass manufacturing, a glass composition, glass with a low inclusion content and a preparation method therefor and use thereof. The composition comprises 50-64 wt. % SiO2, 14-24 wt. % Al2O3, 0-7 wt. % B2O3+P2O5, 0.5-7 wt. % MgO, 1-10 wt. % CaO, 0-9 wt. % SrO, 0.1-14 wt. % BaO, 0.1-5 wt. % ZnO, 0.1-4 wt. % TiO2, 0.1-7 wt. % Y2O3+La2O3+Nd2O3, and