Invention Grant
- Patent Title: Non-aggregating heptamethine cyanine fluorophores for in vivo imaging
-
Application No.: US17179217Application Date: 2021-02-18
-
Publication No.: US11746086B2Publication Date: 2023-09-05
- Inventor: Martin John Schnermann , Michael Philip Luciano , Roger Rauhauser Nani
- Applicant: The USA, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Bethesda
- Assignee: The USA, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The USA, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethesda
- Agency: Klarquist Sparkman, LLP
- Main IPC: C07D209/10
- IPC: C07D209/10 ; A61K49/00 ; G01N21/64 ; G01N33/533 ; G01N33/58 ; C07D403/12 ; C09K11/06
Abstract:
Heptamethine cyanine fluorophore conjugates and conjugate precursors are disclosed. Methods of using the conjugates and conjugate precursors are also disclosed. The disclosed conjugates are neutral zwitterionic molecules and exhibit little or no aggregation.
Public/Granted literature
- US20210198196A1 NON-AGGREGATING HEPTAMETHINE CYANINE FLUOROPHORES FOR IN VIVO IMAGING Public/Granted day:2021-07-01
Information query
