Invention Grant
- Patent Title: Compositions and methods for treating a COVID-19 infection
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Application No.: US17375601Application Date: 2021-07-14
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Publication No.: US11746144B2Publication Date: 2023-09-05
- Inventor: Ivet Bahar , Hongying Cheng , She Zhang , Rebecca Porritt , Moshe Arditi
- Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION , CEDARS-SINAI MEDICAL CENTER
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education,Cedars-Sinai Medical Center
- Current Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education,Cedars-Sinai Medical Center
- Current Assignee Address: US PA Pittsburgh; US CA Los Angeles
- Agency: Meunier Carlin & Curfman LLC
- Main IPC: C07K16/12
- IPC: C07K16/12 ; A61K39/215 ; A61P31/14
Abstract:
Provided herein are methods of treating a COVID-19 infection in a subject, comprising administering to the subject an effective amount of a composition that reduces the superantigen character of SARS-CoV-2 Spike protein. In some embodiments, the compositions are mimetic peptides of the superantigen region. In some embodiments, the compositions are humanized antibodies, such as humanized mAb 6D3, that bind to the superantigen region.
Public/Granted literature
- US20220235119A1 COMPOSITIONS AND METHODS FOR TREATING A COVID-19 INFECTION Public/Granted day:2022-07-28
Information query
