Invention Grant
- Patent Title: Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
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Application No.: US16256931Application Date: 2019-01-24
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Publication No.: US11746336B2Publication Date: 2023-09-05
- Inventor: Satoshi Yuzawa , Leonard Katz , Jay D. Keasling
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Lawrence Berkeley National Laboratory
- Agent Robin C. Chiang
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12P7/42 ; C12P7/26 ; C12N9/04 ; C12N9/16 ; C07K14/36 ; C12N1/21

Abstract:
The present invention provides for a polyketide synthase (PKS) capable of synthesizing a 3-hydroxycarboxylic acid or ketone. The present invention also provides for a host cell comprising the PKS and when cultured produces the 3-hydroxycarboxylic acid or ketone.
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