Invention Grant
- Patent Title: Computer method and system for deriving cell-to-cell spatial proximities
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Application No.: US17671501Application Date: 2022-02-14
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Publication No.: US11747319B2Publication Date: 2023-09-05
- Inventor: Brian Little , Jennifer Bordeaux
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Foley & Lardner LLP
- Main IPC: G01N33/483
- IPC: G01N33/483 ; G01N21/64 ; G01N33/574 ; G01N33/48 ; G16H50/30 ; G16H40/63 ; G16H30/20 ; G06T7/00

Abstract:
The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
Public/Granted literature
- US20220170905A1 COMPUTER METHOD AND SYSTEM FOR DERIVING CELL-TO-CELL SPATIAL PROXIMITIES Public/Granted day:2022-06-02
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